Raffoux C, Streiff F, Blum F, Weber M, Beurey J
C R Seances Soc Biol Fil. 1980;174(1):28-32.
40 unrelated patients with psoriasis vulgaris were studied for their HLA-A, B and DRw antigens phenotypes. All underwent a skin biopsy to confirm diagnosis. Like most of the authors, we observed an increase in B 13 and B 17 antigens (17,50 % and 25 %) whereas in the healthy populations the percentage was (5 % and 6,02 %) respectively. The strongest increase in DRw7 suggest that the psoriasis vulgaris was associated with DRw7 antigens, with a linkage desequilibrium between the B 13 and DRw7 antigens and between the B 17 and DRw7 antigens.
对40例寻常型银屑病患者的HLA - A、B和DRw抗原表型进行了研究。所有患者均接受皮肤活检以确诊。和大多数作者一样,我们观察到B13和B17抗原增加(分别为17.50%和25%),而在健康人群中该百分比分别为(5%和6.02%)。DRw7抗原增加最为明显,提示寻常型银屑病与DRw7抗原相关,且B13与DRw7抗原之间以及B17与DRw7抗原之间存在连锁不平衡。