Hovelius B, Bygren P, Christensen P, Mårdh P A
Scand J Infect Dis Suppl. 1983;39:59-67.
Antibiotics were prescribed for 60% of 1538 patients who consulted a community care centre due to respiratory tract infections. Potential respiratory tract pathogens (betahaemolytic streptococci group A, C, G, Haemophilus influenzae, pneumococci) were isolated from almost half (46%) of the patients. The prescribing of antibiotics was correlated to the isolation of potentially pathogenic bacteria, except for patients with pharyngitis, sinusitis and bronchitis. Betahaemolytic streptococci group A were isolated from 14% of the patients. Recurrence of group A streptococcal infection occurred within 3 months in 24% of patients harbouring such bacteria at the first visit. Poststreptococcal subclinical acute glomerulonephritis (AGN) was diagnosed in 9 (4%) of 220 patients with group A streptococci. The patients with AGN had been treated with antibiotics significantly later than patients without signs of AGN.
在因呼吸道感染前往社区护理中心就诊的1538名患者中，60%的患者使用了抗生素。近一半（46%）的患者分离出潜在的呼吸道病原体（A、C、G组β溶血性链球菌、流感嗜血杆菌、肺炎球菌）。除咽炎、鼻窦炎和支气管炎患者外，抗生素的使用与潜在病原菌的分离相关。14%的患者分离出A组β溶血性链球菌。首次就诊时携带此类细菌的患者中，24%在3个月内发生了A组链球菌感染复发。220例A组链球菌患者中有9例（4%）被诊断为链球菌感染后亚临床急性肾小球肾炎（AGN）。患有AGN的患者使用抗生素的时间明显晚于没有AGN症状的患者。
