Watabe K, Kumanishi T, Ikuta F, Oyake Y
Acta Neuropathol. 1983;61(3-4):173-7. doi: 10.1007/BF00691982.
Tactile-like corpuscles in neurofibroma tissues were examined by the indirect immunoperoxidase method using rabbit anti-S-100 sera. In all five cases examined, positive staining was observed in their constituent cells, both in the flattened cytoplasm and nuclei. On examination of the normal peripheral nervous system, positive staining was exclusively confined to Schwann cells in the nerve bundles and Schwann-related cells such as lamellar cells in the Meissner corpuscle, whereas staining was negative in perineurial cells. Electron-microscopic examination showed ultrastructural similarity between constituent cells of the tactile-like corpuscles in neurofibroma and lamellar cells in the Meissner corpuscle. These findings may indicate Schwannian nature of the tactile-like corpuscles.
采用兔抗S - 100血清，通过间接免疫过氧化物酶法对神经纤维瘤组织中的触觉小体样小体进行检查。在所检查的所有5例病例中，其组成细胞的扁平细胞质和细胞核均观察到阳性染色。在检查正常外周神经系统时，阳性染色仅局限于神经束中的施万细胞以及与施万细胞相关的细胞，如梅克尔小体中的板层细胞，而在神经束膜细胞中染色为阴性。电子显微镜检查显示，神经纤维瘤中触觉小体样小体的组成细胞与梅克尔小体中的板层细胞在超微结构上相似。这些发现可能表明触觉小体样小体具有施万细胞性质。
