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骨关节炎中的经皮电神经刺激:一种治疗选择?

Transcutaneous electrical nerve stimulation in osteoarthrosis: a therapeutic alternative?

作者信息

Lewis D, Lewis B, Sturrock R D

出版信息

Ann Rheum Dis. 1984 Feb;43(1):47-9. doi: 10.1136/ard.43.1.47.

DOI:10.1136/ard.43.1.47
PMID:6364997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001217/
Abstract

Thirty patients with chronic pain due to osteoarthrosis (OA) of the knee were enrolled in a randomised double-blind cross-over trial of self-administered transcutaneous electrical nerve stimulation (TENS) and placebo TENS. Medication was standardised to paracetamol tablets only. As measured on visual analogue scales for pain relief 46% of patients responded to active therapy and 43% to placebo. The length of pain relief during active therapy was significantly longer than that during placebo. At the end of the trial more patients wanted to continue using active TENS in preference to placebo or their original medication. Although most of the parameters observed favoured active TENS, it was not possible to establish its clear superiority over placebo, because the response rate to placebo TENS was high and sustained for at least 3 weeks. This trial suggests that a longer study is required to establish the role of TENS as a therapeutic agent in the treatment of the pain of chronic arthritis.

摘要

30名因膝关节骨关节炎(OA)导致慢性疼痛的患者参与了一项关于自我管理经皮电刺激神经疗法(TENS)和安慰剂TENS的随机双盲交叉试验。药物治疗仅标准化为对乙酰氨基酚片。根据视觉模拟量表测量的疼痛缓解情况,46%的患者对主动治疗有反应,43%的患者对安慰剂有反应。主动治疗期间的疼痛缓解时长显著长于安慰剂治疗期间。试验结束时,更多患者希望继续使用主动TENS,而非安慰剂或其原用药。尽管观察到的大多数参数都有利于主动TENS,但无法确定其明显优于安慰剂,因为安慰剂TENS的反应率很高且持续至少3周。该试验表明,需要进行更长时间的研究来确定TENS作为治疗慢性关节炎疼痛的治疗剂的作用。