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幼犬的C型肉毒中毒

Type C botulism in young dogs.

作者信息

Farrow B R, Murrell W G, Revington M L, Stewart B J, Zuber R M

出版信息

Aust Vet J. 1983 Dec;60(12):374-7. doi: 10.1111/j.1751-0813.1983.tb02852.x.

DOI:10.1111/j.1751-0813.1983.tb02852.x
PMID:6365067
Abstract

A diffuse lower motor neurone paralysis developed in a 6-month-old male Australian cattle dog pup 4 days after it had eaten the carcase of a rotting duck in Centennial Park, Sydney. Two other dogs which ate smaller portions of the same carcase were less severely affected. Clostridium botulinum type C was isolated from and C. botulinum type C toxin was detected in faeces from the severely affected dog. The serum contained 25 LD50 of toxin/ml. The high C. botulinum count and toxin level in the faeces declined progressively during the ensuing weeks, but 114 days after ingesting the carcase C. botulinum type C was still present in faeces and a low toxin titre persisted. Soil, mud and water samples in the area of the duck ponds in the park contained C. botulinum type C spores. Spores and high toxin titres were also found in the intestine of the carcases of 2 birds in the area.

摘要

一只6个月大的雄性澳大利亚牧牛犬幼犬在悉尼百年公园吃了一只腐烂鸭子的尸体4天后,出现了弥漫性下运动神经元麻痹。另外两只吃了同一具尸体较小部分的狗受影响较轻。从这只严重受影响的狗的粪便中分离出了C型肉毒梭菌,并检测到了C型肉毒梭菌毒素。血清中毒素含量为25 LD50/ml。在接下来的几周里,粪便中高含量的肉毒梭菌和毒素水平逐渐下降,但在摄入尸体114天后,粪便中仍存在C型肉毒梭菌,且毒素滴度较低。公园鸭塘区域的土壤、泥浆和水样中含有C型肉毒梭菌孢子。该区域两只鸟类尸体的肠道中也发现了孢子和高毒素滴度。

相似文献

1
Type C botulism in young dogs.幼犬的C型肉毒中毒
Aust Vet J. 1983 Dec;60(12):374-7. doi: 10.1111/j.1751-0813.1983.tb02852.x.
2
[3 cases of Clostridium botulinum type C intoxication in the dog].犬肉毒梭菌C型中毒3例
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Suspected botulism in foxhounds.猎狐犬疑似肉毒中毒。
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Coproexamination for botulinal toxin and clostridium botulinum. A new procedure for laboratory diagnosis of botulism.肉毒杆菌毒素和肉毒梭菌的粪便检查。一种肉毒中毒实验室诊断的新方法。
JAMA. 1977 Oct 24;238(17):1829-32.
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