Miller R W, McKay F W
JAMA. 1984;251(12):1567-70.
Cancer mortality among children in the United States, 1950 through 1979, as evaluated by death certificate diagnoses, revealed dramatic declines primarily in the second half of the 30-year interval. The numbers of deaths of persons younger than 15 years, 1965 through 1979, as compared with the number expected at 1950 rates, fell 50% for leukemia, 32% for non-Hodgkin's lymphoma, 80% for Hodgkin's disease, 50% for bone sarcoma, 68% for kidney cancer, and 31% for all other cancer. There were 17,411 fewer deaths from childhood cancer from 1965 through 1979 than expected at the 1950 rate. Leukemia mortality declined by 8,073 deaths and kidney tumor mortality by 2,393. In data subsequently received for 1980, the decline in rates persisted for leukemia and non-Hodgkin's lymphoma, but the rates for the other four cancer categories seem to have reached a plateau. The reduction in mortality is attributed to improved therapy.
根据死亡证明诊断评估，1950年至1979年美国儿童癌症死亡率显示出显著下降，主要集中在这30年间隔的后半段。1965年至1979年，15岁以下人群的死亡人数与按照1950年死亡率预期的人数相比，白血病下降了50%，非霍奇金淋巴瘤下降了32%，霍奇金病下降了80%，骨肉瘤下降了50%，肾癌下降了68%，所有其他癌症下降了31%。1965年至1979年，儿童癌症死亡人数比按照1950年死亡率预期的少17411人。白血病死亡率下降了8073人，肾肿瘤死亡率下降了2393人。在随后收到的1980年数据中，白血病和非霍奇金淋巴瘤的死亡率持续下降，但其他四类癌症的死亡率似乎已趋于平稳。死亡率的降低归因于治疗的改善。
