Stone M, Fulghum R S
Ann Otol Rhinol Laryngol. 1984 Mar-Apr;93(2 Pt 1):183-6. doi: 10.1177/000348948409300217.
The viable populations of seven species of bacteria were reduced 17% to 99% by treatment with a 3% suspension of human cerumen of the soft or "wet" type. Species tested for susceptibility to cerumen were Staphylococcus aureus, Staphlylococcus epidermidis, Streptococcus pyogenes, Propionibacterium acnes, Corynebacterium spp, Escherichia coli, and Serratia marcescens. The reduction depended upon the species of bacterium and the age of the culture. Pathogenic species appeared to be more susceptible than others, while cultures in logarithmic growth were more susceptible than stationary phase cultures to the bactericidal activity of wet cerumen. There appeared to be little difference in the bactericidal activity between the two lots of cerumen used. The bactericidal activity of wet cerumen was found to be quite similar to that of dry cerumen as reported earlier in the literature.
用3%的软质或“湿性”人耳垢悬液处理后,7种细菌的活菌数量减少了17%至99%。检测耳垢敏感性的细菌种类有金黄色葡萄球菌、表皮葡萄球菌、化脓性链球菌、痤疮丙酸杆菌、棒状杆菌属、大肠杆菌和粘质沙雷氏菌。减少程度取决于细菌种类和培养物的菌龄。致病菌种似乎比其他菌种更易受影响,而对数生长期的培养物比稳定期培养物对湿性耳垢的杀菌活性更敏感。所使用的两批耳垢之间的杀菌活性似乎没有太大差异。湿性耳垢的杀菌活性被发现与文献中先前报道的干性耳垢的杀菌活性非常相似。