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人耳垢的非极性脂质成分。

Non-polar lipid components of human cerumen.

作者信息

Stránský Karel, Valterová Irena, Kofroňová Edita, Urbanová Klára, Zarevúcka Marie, Wimmer Zdeněk

机构信息

Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo náměstí 2, 16610, Prague 6, Czech Republic.

出版信息

Lipids. 2011 Aug;46(8):781-8. doi: 10.1007/s11745-011-3564-y. Epub 2011 May 6.

DOI:10.1007/s11745-011-3564-y
PMID:21547555
Abstract

Human cerumen was separated by column chromatography into the following groups of compounds: hydrocarbons, squalene, wax esters and cholesterol esters, triacylglycerols, free fatty acids, free fatty alcohols, monoacylglycerols, free cholesterol, free sterols, and free hydroxy acids. The groups of compounds obtained were examined in detail by gas chromatography and gas chromatography-mass spectrometry. In total, about one thousand compounds have been identified.

摘要

人耳垢通过柱色谱法分离为以下几类化合物

烃类、角鲨烯、蜡酯和胆固醇酯、三酰甘油、游离脂肪酸、游离脂肪醇、单酰甘油、游离胆固醇、游离甾醇和游离羟基酸。对所得到的各类化合物通过气相色谱法和气相色谱-质谱联用仪进行了详细检测。总共已鉴定出约一千种化合物。

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Non-polar lipid components of human cerumen.人耳垢的非极性脂质成分。
Lipids. 2011 Aug;46(8):781-8. doi: 10.1007/s11745-011-3564-y. Epub 2011 May 6.
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本文引用的文献

1
Identification and analysis of wax esters by mass spectrometry.通过质谱法鉴定和分析蜡酯
Lipids. 1971 Jul;6(7):502-7. doi: 10.1007/BF02531236.
2
Double-bond location in monounsaturated fatty acids by dimethyl disulfide derivatization and mass spectrometry: Application to analysis of fatty acids in pheromone glands of four lepidoptera.二硫二甲醚衍生化和质谱法测定单不饱和脂肪酸中的双键位置：在四种鳞翅目昆虫信息素腺脂肪酸分析中的应用。
J Chem Ecol. 1985 Mar;11(3):265-77. doi: 10.1007/BF01411414.
3
Protein isolation from ear wax made easy.轻松从耳垢中提取蛋白质。
植物蜡酯合成酶的异源表达及特性分析
Metabolites. 2022 Jun 22;12(7):577. doi: 10.3390/metabo12070577.
4
Two-Dimensional Gas Chromatographic and Mass Spectrometric Characterization of Lipid-Rich Biological Matrices-Application to Human Cerumen (Earwax).富含脂质生物基质的二维气相色谱和质谱表征——应用于人类耳垢（耵聍）
ACS Omega. 2021 Dec 27;7(1):230-239. doi: 10.1021/acsomega.1c04535. eCollection 2022 Jan 11.
5
Hearing healthcare gaps in LMICS: snapshot from a semi-urban community in Nigeria.中低收入国家的听力保健差距：尼日利亚一个半城市社区的快照。
Afr Health Sci. 2021 Jun;21(2):912-918. doi: 10.4314/ahs.v21i2.53.
6
Mass Spectrometric Analysis of Meibomian Gland Lipids.泪腺脂质的质谱分析。
Methods Mol Biol. 2021;2306:157-170. doi: 10.1007/978-1-0716-1410-5_11.
7
Banji's test: A new diagnostic test of ear wax impaction.班吉氏试验：一种新的耵聍栓塞诊断试验。
J Family Med Prim Care. 2018 Nov-Dec;7(6):1253-1255. doi: 10.4103/jfmpc.jfmpc_152_18.
8
Insights into cerumen and application in diagnostics: past, present and future prospective.耳垢的研究进展及其在诊断中的应用：过去、现在和未来展望。
Biochem Med (Zagreb). 2017 Oct 15;27(3):030503. doi: 10.11613/BM.2017.030503.
9
Earwax Impaction: Symptoms, Predisposing Factors and Perception among Nigerians.耳垢堵塞：尼日利亚人的症状、诱发因素及认知
J Family Med Prim Care. 2014 Oct-Dec;3(4):379-82. doi: 10.4103/2249-4863.148116.
10
Identification of volatile organic compounds in human cerumen.人耳垢中挥发性有机化合物的鉴定
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 15;953-954:48-52. doi: 10.1016/j.jchromb.2014.01.043. Epub 2014 Feb 5.
Eur Arch Otorhinolaryngol. 2009 Nov;266(11):1699-702. doi: 10.1007/s00405-009-0960-5. Epub 2009 Apr 4.
4
Quantitative evaluation of sebum lipid components with nuclear magnetic resonance.利用核磁共振对皮脂脂质成分进行定量评估。
J Lipid Res. 2008 Mar;49(3):686-92. doi: 10.1194/jlr.D700035-JLR200. Epub 2007 Dec 19.
5
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Rapid Commun Mass Spectrom. 2006;20(23):3586-94. doi: 10.1002/rcm.2770.
6
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J Chromatogr A. 2006 Sep 22;1128(1-2):208-19. doi: 10.1016/j.chroma.2006.06.035. Epub 2006 Jul 3.
7
Analysis of triacylglycerols in fat body of bumblebees by chromatographic methods.用色谱法分析熊蜂脂肪体中的三酰甘油。
J Chromatogr A. 2006 Jan 6;1101(1-2):226-37. doi: 10.1016/j.chroma.2005.10.001. Epub 2005 Oct 24.
8
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9
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Ann Otol Rhinol Laryngol. 1964 Mar;73:218-21.
10
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Scand J Clin Lab Invest. 1962;14:368-72. doi: 10.3109/00365516209079722.