• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Intestinal and liver toxicity of antineoplastic drugs.抗肿瘤药物的肠道和肝脏毒性
West J Med. 1984 Feb;140(2):250-9.
2
Metabolic causes of nephrolithiasis.肾结石的代谢性病因。
West J Med. 1983 Apr;138(4):541-5.
3
Fever and pulmonary infiltrates in a patient with a renal transplant.一名肾移植患者出现发热和肺部浸润。
West J Med. 1984 Jun;140(6):914-20.
4
Human obesity. Exploding the myths.人类肥胖症。破除迷思。
West J Med. 1990 Oct;153(4):421-8.
5
Beyond the physicians' reference. The ethics of active euthanasia.超越医生的参考范畴。主动安乐死的伦理问题。
West J Med. 1988 Aug;149(2):195-8.
6
Common causes of cardiac emboli--left ventricular thrombi and atrial fibrillation.心脏栓子的常见原因——左心室血栓和心房颤动。
West J Med. 1989 Aug;151(2):172-9.
7
The neurologic sequelae of cardiac arrest.心脏骤停的神经后遗症。
West J Med. 1987 Aug;147(2):175-80.
8
N-of-1 clinical trials. A technique for improving medical therapeutics.单病例临床试验。一种改善医学治疗效果的技术。
West J Med. 1990 Jan;152(1):52-6.
9
Dizzy patients. Diagnosis and treatment.眩晕患者。诊断与治疗。
West J Med. 1995 Jan;162(1):37-42.
10
Increased erythrocyte sedimentation rate and a splenic mass.红细胞沉降率升高及脾脏肿大。
West J Med. 1994 Dec;161(6):585-91.

引用本文的文献

1
Multi-tissue metabolomics analysis reveals susceptible factors for chemotherapy-induced hepatotoxicity in colorectal cancer patients.多组织代谢组学分析揭示了结直肠癌患者化疗诱导肝毒性的易感因素。
Front Pharmacol. 2025 Apr 4;16:1517446. doi: 10.3389/fphar.2025.1517446. eCollection 2025.
2
Imaging of the chemotherapy-induced hepatic damage: Yellow liver, blue liver, and pseudocirrhosis.化疗引起的肝损伤的影像学表现：黄肝、蓝肝和假性肝硬化。
World J Gastroenterol. 2021 Dec 14;27(46):7866-7893. doi: 10.3748/wjg.v27.i46.7866.
3
The Use of Imaging in the Prediction and Assessment of Cancer Treatment Toxicity.影像学在癌症治疗毒性预测与评估中的应用
Diagnostics (Basel). 2017 Jul 20;7(3):43. doi: 10.3390/diagnostics7030043.
4
Chemotherapy induced liver abnormalities: an imaging perspective.化疗引起的肝脏异常：影像学视角
Clin Mol Hepatol. 2014 Sep;20(3):317-26. doi: 10.3350/cmh.2014.20.3.317.
5
Imaging of complications of oncological therapy in the gastrointestinal system.消化系统肿瘤治疗相关并发症的影像学表现
Cancer Imaging. 2012 May 7;12(1):163-72. doi: 10.1102/1470-7330.2012.0014.
6
Effectiveness of Traditional Chinese Medicine for Liver Protection and Chemotherapy Completion among Cancer Patients.中医药对癌症患者肝脏保护和化疗完成的有效性。
Evid Based Complement Alternat Med. 2011;2011:291843. doi: 10.1093/ecam/nep185. Epub 2011 Jun 7.
7
Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.儿童和成人群体癌症幸存者的肝胆晚期效应：来自儿童肿瘤学组的报告。
Pediatr Blood Cancer. 2010 May;54(5):663-9. doi: 10.1002/pbc.22265.
8
Tumor-related dysmotility: gastrointestinal dysmotility syndromes associated with tumors.肿瘤相关的运动障碍：与肿瘤相关的胃肠运动障碍综合征
Dig Dis Sci. 1998 Jul;43(7):1369-401. doi: 10.1023/a:1018853106696.
9
Types, causes, and therapies of hepatitis occurring in liver transplant recipients.肝移植受者中发生的肝炎的类型、病因及治疗方法。
Dig Dis Sci. 1993 Mar;38(3):449-56. doi: 10.1007/BF01316498.
10
Antineoplastic drugs in 1990. A review (Part II).1990年的抗肿瘤药物。综述（第二部分）。
Drugs. 1990 May;39(5):652-73. doi: 10.2165/00003495-199039050-00003.

本文引用的文献

1
Subcutaneous fat necrosis with acute hemorrhagic pancreatitis-a case in a child with steroid-resistant nephrosis treated with 6-mercaptopurine.皮下脂肪坏死合并急性出血性胰腺炎——1例接受6-巯基嘌呤治疗的激素抵抗型肾病患儿病例
Calif Med. 1967 Jan;106(1):58-63.
2
Nitrogen mustards in the treatment of neoplastic disease.氮芥类药物在肿瘤疾病治疗中的应用
Adv Intern Med. 1950;4:1-75.
3
HEPATOTOXICITY OF MERCAPTOPURINE.巯嘌呤的肝毒性
JAMA. 1964 Jun 1;188:802-6. doi: 10.1001/jama.1964.03060350028007.
4
A CONTROLLED CLINICAL EVALUATION OF ANTIEMETIC DRUGS.抗呕吐药物的对照临床评价
JAMA. 1963 Oct 12;186:116-8. doi: 10.1001/jama.1963.03710020036011.
5
A comparative study of eleven anti-emetic drugs in dogs.犬用十一种止吐药的比较研究。
Can Anaesth Soc J. 1962 Sep;9:399-407. doi: 10.1007/BF03019133.
6
Morphologic alterations induced by methotrexate in the mucosa of human proximal intestine. II. Electron microscopic observations.甲氨蝶呤对人近端小肠黏膜的形态学改变。II. 电子显微镜观察结果
Gastroenterology. 1962 Oct;43:407-24.
7
Urethane-induced hepatic failure in man.氨基甲酸乙酯诱发的人类肝衰竭。
Am J Med. 1960 Mar;28:476-81. doi: 10.1016/0002-9343(60)90178-9.
8
Toxic complications of treatment with 6-mercaptopurine; two cases with hepatic necrosis and intestinal ulceration.6-巯基嘌呤治疗的毒性并发症；两例肝坏死和肠溃疡病例。
Br Med J. 1960 Feb 6;1(5170):393-5. doi: 10.1136/bmj.1.5170.393.
9
Studies on the mechanism of action of cytoxan. Evidence of activation in vivo and in vitro.环磷酰胺作用机制的研究。体内和体外激活的证据。
Cancer Res. 1961 Jan;21:57-63.
10
Hepatitis in association with prolonged 6-mercaptopurine therapy.与长期6-巯基嘌呤治疗相关的肝炎。
Blood. 1959 Jan;14(1):80-90.

抗肿瘤药物的肠道和肝脏毒性

Intestinal and liver toxicity of antineoplastic drugs.

作者信息

McDonald G B, Tirumali N

出版信息

West J Med. 1984 Feb;140(2):250-9.

PMID:6375139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1021607/
Abstract

This discussion was selected from the weekly Grand Rounds in the Department of Medicine, University of Washington, Seattle. Taken from a transcription, it has been edited by Drs Paul G. Ramsey, Assistant Professor of Medicine, and Philip J. Fialkow, Professor and Chairman of the Department of Medicine.

摘要

本次讨论选自华盛顿大学西雅图分校医学院的每周大查房。该内容摘自一份文字记录，由医学助理教授保罗·G·拉姆齐博士和医学系教授兼系主任菲利普·J·菲亚尔科夫博士编辑。