Kagan E Z, Vasil'ev V K, Bykova M A, Berezina E K
Antibiotiki. 1978 Mar;23(3):257-9.
Technology of 0.1 per cent gentamicin ointment production was developed. The ointment base consisted of vaseline and parafin (95:5). Pharmacokinetics and innocuousness of the gentamicin ointment were studied. It was shown that the ointment provided gentamicin diffusion through the skin utegument during a long period of time. Histological studies showed no local irritating effect of the ointment on the skin in its local use.
研发出了0.1%庆大霉素软膏的生产工艺。软膏基质由凡士林和石蜡（95:5）组成。对庆大霉素软膏的药代动力学和无害性进行了研究。结果表明，该软膏能在很长一段时间内使庆大霉素透过皮肤表皮扩散。组织学研究表明，该软膏局部使用时对皮肤无局部刺激作用。
