食管静脉曲张患者的预防性门静脉减压手术。中期报告。
Prophylactic portal nondecompression surgery in patients with esophageal varices. An interim report.
作者信息
Inokuchi K
出版信息
Ann Surg. 1984 Jul;200(1):61-5. doi: 10.1097/00000658-198407000-00010.
Abstract
This is an interim report of a prospective controlled study to evaluate prophylactic surgery in 112 patients with portal hypertension and esophageal varices treated since 1980. Methods of operation were confined to those with the least influence on portal circulation, namely selective shunts and nonshunting direct interruption procedures. The bleeding rates were 19.2% in the medical group and none in the surgical group (p less than 0.01). The mortality in the medical group in case of first bleeding was 50%. Operative mortality was 3.3%. There was no difference in the survival rate between the two groups at the time of 2 years follow-up. Prophylactic surgery led to a prevention of esophageal bleeding without any increase in the mortality rates.
摘要
这是一项前瞻性对照研究的中期报告，该研究旨在评估自1980年以来接受治疗的112例门静脉高压症和食管静脉曲张患者的预防性手术。手术方法仅限于对门静脉循环影响最小的那些方法，即选择性分流术和非分流直接阻断手术。药物治疗组的出血率为19.2%，手术组则无出血（p<0.01）。药物治疗组首次出血时的死亡率为50%。手术死亡率为3.3%。两组在2年随访时的生存率无差异。预防性手术可预防食管出血，且死亡率无任何增加。
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