Liebowitz M R, Quitkin F M, Stewart J W, McGrath P J, Harrison W, Rabkin J G, Tricamo E, Markowitz J S, Klein D F
J Clin Psychiatry. 1984 Jul;45(7 Pt 2):22-5.
Sixty patients meeting specific criteria for atypical depression completed 6 weeks of double-blind, randomly assigned treatment with phenelzine, imipramine, or placebo. Patients who had a history of spontaneous panic attacks or hysteriod dysphoric features showed extremely low placebo-response rates, moderate responses to imipramine, and high rates of response to phenelzine. Conversely, patients without such features responded moderately well to all three treatments. Based on preliminary data, MAOI-specific atypical depression does appear to exist, although in more delimited forms than previously recognized.
