Gretz N, Korb E, Strauch M
Kidney Int Suppl. 1983 Dec;16:S263-7.
In this prospective controlled study, a 30-g protein-restricted diet supplemented by keto acids resulted in a delayed rate of progression of chronic renal failure. The effect of this treatment differed according to the underlying renal disease. The rate of progression of chronic renal failure was delayed by a factor of at least 2. A need for long-term observations to quantify the effectiveness of this therapy is shown. A new pragmatic approach to the evaluation of long-term studies in patients with chronic renal failure is demonstrated.
在这项前瞻性对照研究中，一种补充了酮酸的30克蛋白质限制饮食可延缓慢性肾衰竭的进展速度。这种治疗的效果因潜在的肾脏疾病而异。慢性肾衰竭的进展速度延缓了至少2倍。研究表明需要进行长期观察以量化这种疗法的有效性。展示了一种评估慢性肾衰竭患者长期研究的新实用方法。
