Soong H K, Kenyon K R
Ophthalmology. 1984 May;91(5):479-83. doi: 10.1016/s0161-6420(84)34273-7.
During the past 3 years, 12 patients (14 eyes) were encountered with severe reactions to virgin silk sutures used in cataract surgery. These reactions included nodular episcleritis, peripheral corneal ulceration, and wound necrosis with dehiscence, sometimes resulting in endophthalmitis or epithelial downgrowth. Conjunctival and scleral histopathologic studies in four eyes showed acute and chronic inflammation with multinucleated giant cells. Successful treatment included removal of the virgin silk sutures, resuturing with 10-0 nylon sutures, securing the necrotic tissue with cyanoacrylate adhesive, and resection of the inflamed superior conjunctiva. All four patients who had bilateral cataract surgery experienced either simultaneous flare-ups of both eyes or accelerated reactions after surgery on the second eye, which suggests a possible role of prior sensitization.
在过去3年中，我们遇到了12例患者（14只眼），他们对白内障手术中使用的生丝缝线出现了严重反应。这些反应包括结节性表层巩膜炎、周边角膜溃疡以及伴有裂开的伤口坏死，有时会导致眼内炎或上皮内生。对4只眼进行的结膜和巩膜组织病理学研究显示有急性和慢性炎症，并伴有多核巨细胞。成功的治疗方法包括拆除生丝缝线，用10-0尼龙缝线重新缝合，用氰基丙烯酸酯粘合剂固定坏死组织，以及切除发炎的上结膜。所有接受双眼白内障手术的4例患者，要么双眼同时出现炎症发作，要么在第二只眼手术后反应加速，这表明先前致敏可能起到了作用。
