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空肠弯曲菌:人类食物感染的重要病原体。综述

[Campylobacter jejuni: an important causative agent of food infection in man. An overview].

作者信息

Oosterom J

出版信息

Tijdschr Diergeneeskd. 1984 Jun 1;109(11):446-55.

PMID:6377580
Abstract

Since a few years, Campylobacter jejuni has been identified as an important cause of acute enteritis in man. Various studies showed that Campylobacter enteritis is as common as salmonellosis, and that the symptoms often are even more severe. That this species of bacterium was not discovered until recently, was due in part to the fact that unusual methods of isolation are required; for instance, Campylobacter jejuni will only grow in a micro-aerophilic atmosphere. Campylobacteriosis was found to be a foodborne infection in the majority of cases. The organism was isolated from a large number of species of wild and domesticated animals, which, as in the case of Salmonella, are mainly asymptomatic carriers. Of farm animals, poultry and pigs are most frequently infected. The most important sources of human infection are poultry meat, unpasteurized milk, inadequately treated drinking water and, as a direct source, dogs with enteritis. Only poultry was found to play a role in the Netherlands. Pork is mostly not contaminated as Campylobacter dies during cooling of pig carcasses, death being due to the drying effect of forced ventilation. The sensitivity of Campylobacter to dry conditions, in conjunction with its inability to multiply below 30 degrees C, means that the mechanism of cross contamination, which is such an important factor in the epidemiology of Salmonella, is of minor significance in Campylobacter.

摘要

近年来,空肠弯曲菌已被确认为人类急性肠炎的重要病因。多项研究表明,弯曲菌肠炎与沙门氏菌病一样常见,而且症状往往更为严重。这种细菌直到最近才被发现,部分原因是需要采用特殊的分离方法;例如,空肠弯曲菌仅在微需氧环境中生长。弯曲菌病在大多数情况下被发现是一种食源性感染。该病原体从大量野生动物和家畜物种中分离出来,与沙门氏菌情况一样,这些动物主要是无症状携带者。在家畜中,家禽和猪最常受到感染。人类感染的最重要来源是禽肉、未经巴氏消毒的牛奶、处理不当的饮用水,以及作为直接来源的患肠炎的狗。在荷兰,仅发现家禽起到了传播作用。猪肉大多未受污染,因为弯曲菌在猪胴体冷却过程中死亡,死亡原因是强制通风的干燥作用。弯曲菌对干燥条件的敏感性,加上其在30摄氏度以下无法繁殖,这意味着在沙门氏菌流行病学中如此重要的交叉污染机制,在弯曲菌中意义不大。

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