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[菌血症在小鼠宋内志贺菌感染中免疫记忆抑制发展中的意义]

[Significance of bacteremia in the development of immunological memory suppression in Shigella sonnei infection in mice].

作者信息

Frolov A F, Borisov V A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1984 Apr(4):97-101.

PMID:6377773
Abstract

Experiments on mice infected intraperitoneally with S. sonnei have revealed that the level of bacteriemia is directly related to the duration of the blocking of immunological memory constituting the basis of secondary humoral and cell-mediated immune response. The transfer of syngeneic splenocytes from immunized mice has demonstrated that virulent S. sonnei directly affect the immunological memory cells.

摘要

对经腹腔感染宋内志贺菌的小鼠进行的实验表明,菌血症水平与构成二次体液免疫和细胞介导免疫反应基础的免疫记忆阻断持续时间直接相关。来自免疫小鼠的同基因脾细胞转移实验表明,有毒力的宋内志贺菌直接影响免疫记忆细胞。

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[Significance of bacteremia in the development of immunological memory suppression in Shigella sonnei infection in mice].[菌血症在小鼠宋内志贺菌感染中免疫记忆抑制发展中的意义]
Zh Mikrobiol Epidemiol Immunobiol. 1984 Apr(4):97-101.
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Immune processes in the course of infection with dysentery bacilli. III. Protective activity of spleen cells and serum from mice immunized with killed dysentery bacilli.痢疾杆菌感染过程中的免疫过程。III. 用灭活痢疾杆菌免疫的小鼠脾脏细胞和血清的保护活性。
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Shigella sonnei bacteremia. Unusual antibody response from immunosuppressive therapy following renal transplantation.宋内志贺菌菌血症。肾移植后免疫抑制治疗引起的异常抗体反应。
Urology. 1974 Aug;4(2):198-200. doi: 10.1016/0090-4295(74)90333-1.