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[从不同类型临床材料中分离出的变形杆菌菌株对抗生素的反应]

[Response to antibiotics of Proteus strains isolated from different types of clinical material].

作者信息

Ovetchin P V, Tsyganenko A Ia

出版信息

Antibiotiki. 1984 Apr;29(4):272-5.

PMID:6378080
Abstract

The data on the study of the antibiotic response to 42 Proteus strains isolated from different sources in the hospitals of Kharkov are presented. The isolates belonged to P. mirabilis and P. vulgaris. Many strains were resistant to gentamicin, ampicillin and carbenicillin irrespective of the isolation source. 58.0 and 90.3 per cent of the strains isolated from patients with intestinal infections, 66.6 and 100 per cent of the strains isolated from patients with otitis, 33.3 and 66.6 per cent of the strains isolated from patients with bronchopulmonary affections and 100 and 100 per cent of the strains isolated from patients with urological diseases were resistant to gentamicin and carbenicillin, respectively. As for ampicillin, the respective figures were 74.2, 66.6, 66.6 and 100 per cent. All the strains of P. vulgaris isolated from patients with otitis, urological diseases and bronchopulmonary affections were resistant to ampicillin. The MIC of carbenicillin for all the strains except 4 indole-positive strains of P. vulgaris isolated from the faeces and bronchial excreta was much higher than the borderline values.

摘要

本文展示了对从哈尔科夫市医院不同来源分离出的42株变形杆菌进行抗生素反应研究的数据。这些分离菌株属于奇异变形杆菌和普通变形杆菌。许多菌株对庆大霉素、氨苄青霉素和羧苄青霉素耐药,与分离来源无关。从肠道感染患者中分离出的菌株,分别有58.0%和90.3%对庆大霉素和羧苄青霉素耐药;从耳部感染患者中分离出的菌株,分别有66.6%和100%对庆大霉素和羧苄青霉素耐药;从支气管肺部疾病患者中分离出的菌株,分别有33.3%和66.6%对庆大霉素和羧苄青霉素耐药;从泌尿系统疾病患者中分离出的菌株,分别有100%和100%对庆大霉素和羧苄青霉素耐药。至于氨苄青霉素,相应的比例分别为74.2%、66.6%、66.6%和100%。从耳部感染、泌尿系统疾病和支气管肺部疾病患者中分离出的所有普通变形杆菌菌株均对氨苄青霉素耐药。除从粪便和支气管排泄物中分离出的4株吲哚阳性普通变形杆菌外,所有菌株对羧苄青霉素的最低抑菌浓度均远高于临界值。

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