痤疮丙酸杆菌和颗粒丙酸杆菌中卟啉生成的比较研究。
Comparative studies of porphyrin production in Propionibacterium acnes and Propionibacterium granulosum.
作者信息
Lee W L, Shalita A R, Poh-Fitzpatrick M B
出版信息
J Bacteriol. 1978 Feb;133(2):811-5. doi: 10.1128/jb.133.2.811-815.1978.
Abstract
Porphyrin production by Propionibacterium acnes and that by Propionibacterium granulosum were compared. Porphyrin synthesized by both organisms was identified as coproporphyrin III on the bases of absorption and fluorescence spectra and behavior on paper chromatography and thin-layer chromatography. Quantitative, rather than qualitative, differences in production were found between these organisms. In general, P. granulosum produced significantly greater amounts (P less than 0.001) of porphyrin than did P. acnes. delta-Aminolevulinic acid synthetase appeared to be the rate-limiting enzyme of the heme biosynthetic pathway in both organisms. The increased porphyrin production in P. granulosum is apparently associated with increased delta-aminolevulinic acid synthetase activity.
摘要
对痤疮丙酸杆菌和颗粒丙酸杆菌产生卟啉的情况进行了比较。根据吸收光谱、荧光光谱以及在纸色谱和薄层色谱上的表现，确定这两种微生物合成的卟啉均为粪卟啉III。发现这两种微生物在卟啉产生量上存在定量而非定性的差异。总体而言，颗粒丙酸杆菌产生的卟啉量显著多于痤疮丙酸杆菌（P<0.001）。δ-氨基乙酰丙酸合成酶似乎是这两种微生物血红素生物合成途径中的限速酶。颗粒丙酸杆菌中卟啉产量的增加显然与δ-氨基乙酰丙酸合成酶活性的增加有关。
相似文献
1
Comparative studies of porphyrin production in Propionibacterium acnes and Propionibacterium granulosum.
J Bacteriol. 1978 Feb;133(2):811-5. doi: 10.1128/jb.133.2.811-815.1978.
2
Porphyrin Production and Regulation in Cutaneous Propionibacteria.
mSphere. 2020 Jan 15;5(1):e00793-19. doi: 10.1128/mSphere.00793-19.
3
Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light.
FEMS Immunol Med Microbiol. 2003 Jan 21;35(1):17-24. doi: 10.1111/j.1574-695X.2003.tb00644.x.
4
Influence of pH on porphyrin production in Propionibacterium acnes.
Arch Dermatol Res. 1984;276(6):396-400. doi: 10.1007/BF00413361.
5
The temperature dependence of porphyrin production in Propionibacterium acnes after incubation with 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA).
Photochem Photobiol Sci. 2006 Jan;5(1):66-72. doi: 10.1039/b512837d. Epub 2005 Nov 10.
6
Accumulation of porphyrins in Propionibacterium acnes by 5-aminolevulinic acid and its esters.
Photodiagnosis Photodyn Ther. 2017 Sep;19:167-169. doi: 10.1016/j.pdpdt.2017.06.004. Epub 2017 Jun 15.
7
[Porphyrinsynthesis by propionibacterium acnes (author's transl)].
Arch Dermatol Res (1975). 1977 Aug 22;259(2):169-76. doi: 10.1007/BF00557958.
8
In situ assessment of porphyrin photosensitizers in Propionibacterium acnes.
Z Naturforsch C J Biosci. 2004 Jan-Feb;59(1-2):93-8. doi: 10.1515/znc-2004-1-219.
9
Comparative study of the bactericidal effects of 5-aminolevulinic acid with blue and red light on Propionibacterium acnes.
J Dermatol. 2011 Jul;38(7):661-6. doi: 10.1111/j.1346-8138.2010.01094.x. Epub 2010 Nov 3.
10
Over-production of porphyrins and heme in heterotrophic bacteria.
Z Naturforsch C Biosci. 1975 May-Jun;30(3):425-6. doi: 10.1515/znc-1975-5-624.
引用本文的文献
1
Safety Evaluation of Topical Products Containing Live Cultures and Ferment of Cutibacterium Acnes Subspecies Defendens Strain XYCM42 in Individuals Predisposed to Acne Vulgaris.
J Clin Aesthet Dermatol. 2025 May 1;18(5):44-53.
2
State-of-the-Art in Skin Fluorescent Photography for Cosmetic and Skincare Research: From Molecular Spectra to AI Image Analysis.
Life (Basel). 2024 Oct 6;14(10):1271. doi: 10.3390/life14101271.
3
Spectral characterization of a blue light-emitting micro-LED platform on skin-associated microbial chromophores.
Biomed Opt Express. 2024 Apr 19;15(5):3200-3215. doi: 10.1364/BOE.522867. eCollection 2024 May 1.
4
Perialar intertrigo in children and adolescents: A multicenter prospective study of 41 cases.
Pediatr Dermatol. 2022 Sep;39(5):702-707. doi: 10.1111/pde.15036. Epub 2022 Jun 14.
5
Solution Structure of the -Specific Protein RoxP and Insights Into Its Antioxidant Activity.
Front Cell Infect Microbiol. 2022 Feb 11;12:803004. doi: 10.3389/fcimb.2022.803004. eCollection 2022.
6
Porphyrins produced by acneic strains activate the inflammasome by inducing K leakage.
iScience. 2021 May 21;24(6):102575. doi: 10.1016/j.isci.2021.102575. eCollection 2021 Jun 25.
7
Red Fluorescence of European Hedgehog (Erinaceus europaeus) Spines Results from Free-Base Porphyrins of Potential Microbial Origin.
J Chem Ecol. 2021 Jun;47(6):588-596. doi: 10.1007/s10886-021-01279-6. Epub 2021 May 4.
8
Comparative Study Of Photodynamic Therapy With Riboflavin-Tryptophan Gel And 13% 5-Aminolevulinic Acid In The Treatment Of Mild To Moderate Acne Vulgaris.
Clin Cosmet Investig Dermatol. 2019 Nov 5;12:805-814. doi: 10.2147/CCID.S227737. eCollection 2019.
9
Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:X.
Diagnostics (Basel). 2019 Feb 26;9(1):22. doi: 10.3390/diagnostics9010022.
10
Measuring acne using Coproporphyrin III, Protoporphyrin IX, and lesion-specific inflammation: an exploratory study.
Arch Dermatol Res. 2017 Apr;309(3):159-167. doi: 10.1007/s00403-017-1718-3. Epub 2017 Feb 8.
本文引用的文献
1
The isolation of coproporphyrin III from Corynebacterium diphtheriae culture filtrates.
Biochem J. 1948;43(2):191-3.
2
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75.
3
Paper chromatographic separation of the coproporphyrin isomers I and III.
Scand J Clin Lab Invest. 1958;10(3):319-22.
4
Kinetic studies of pigment synthesis by non-sulfur purple bacteria.
J Cell Comp Physiol. 1957 Feb;49(1):25-68. doi: 10.1002/jcp.1030490104.
5
The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine.
J Biol Chem. 1956 Mar;219(1):435-46.
6
7
Cell wall composition and deoxyribonucleic acid similarities among the anaerobic coryneforms, classical propionibacteria, and strains of Arachnia propionica.
J Bacteriol. 1972 Mar;109(3):1047-66. doi: 10.1128/jb.109.3.1047-1066.1972.
8
Formation of protoporphyrin from coproporphyrinogen in extracts of various bacteria.
J Bacteriol. 1970 May;102(2):398-403. doi: 10.1128/jb.102.2.398-403.1970.
9
Differentiation of two groups of Corynebacterium acnes.
J Bacteriol. 1970 Feb;101(2):392-7. doi: 10.1128/jb.101.2.392-397.1970.
10
Rapid quantitative assay for erythrocyte porphyrins.
Arch Dermatol. 1974 Aug;110(2):225-30.
Zotero 插件