Oken M M
Med Clin North Am. 1984 May;68(3):757-87. doi: 10.1016/s0025-7125(16)31127-0.
Multiple myeloma is a malignant neoplasm of plasma cells involving bone and bone marrow, frequently leading to extensive skeletal destruction, bone marrow failure, renal dysfunction, and problems related to the monoclonal myeloma proteins. Vigilant supportive care and effective chemotherapy can prolong survival and improve the quality of life in most patients.
多发性骨髓瘤是一种累及骨骼和骨髓的浆细胞恶性肿瘤，常导致广泛的骨骼破坏、骨髓衰竭、肾功能不全以及与单克隆骨髓瘤蛋白相关的问题。警惕的支持治疗和有效的化疗可延长大多数患者的生存期并改善生活质量。
