合成拟除虫菊酯在鼠伤寒沙门氏菌菌株和V79中国仓鼠细胞中无致突变性。
Lack of mutagenicity of synthetic pyrethroids in Salmonella typhimurium strains and in V79 Chinese hamster cells.
作者信息
Pluijmen M, Drevon C, Montesano R, Malaveille C, Hautefeuille A, Bartsch H
出版信息
Mutat Res. 1984 Jul;137(1):7-15. doi: 10.1016/0165-1218(84)90106-x.
PMID:6379439
Abstract
Seven pyrethroids, i.e., cypermethrin, permethrin, deltamethrin, bioresmethrin, resmethrin, cismethrin and fenvalerate, were not found to be mutagenic in (a) Salmonella typhimurium strains TA100 or TA98 in the presence or absence of a rat liver activation system using the plate incorporation assay and fluctuation tests, or (b) V79 Chinese hamster cells in the presence or absence of hepatocytes.
摘要
七种拟除虫菊酯，即氯氰菊酯、氯菊酯、溴氰菊酯、生物苄呋菊酯、苄呋菊酯、顺式氯氰菊酯和氰戊菊酯，在以下实验中未发现具有致突变性：(a) 使用平板掺入试验和波动试验，在有或无大鼠肝脏活化系统的情况下，对鼠伤寒沙门氏菌TA100或TA98菌株进行检测；(b) 在有或无肝细胞的情况下，对V79中国仓鼠细胞进行检测。
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