Wafin F, Valindas E, Wuolijoki E
Clin Rheumatol. 1984 Mar;3(1):67-70. doi: 10.1007/BF02715698.
The efficacy and tolerability of 100 mg suppositories of diclofenac sodium (Voltaren) and indomethacin were investigated in relieving symptoms of rheumatoid arthritis. Thirty patients were included in a double-blind, cross-over study for two weeks - six days with diclofenac suppositories, following two days with placebo and six days with indomethacin. Diclofenac sodium and indomethacin were given in random order. Both treatments improved the status of the disease as compared with the situation before the treatment (p less than 0.01). No statistically significant difference was found between the efficacy of indomethacin and diclofenac sodium, as regards both the doctor's and the patient's global assessments. The two treatments were equally well tolerated.
研究了双氯芬酸钠（扶他林）100毫克栓剂和吲哚美辛缓解类风湿性关节炎症状的疗效和耐受性。30名患者纳入一项双盲交叉研究，为期两周，先使用双氯芬酸栓剂六天，接着使用安慰剂两天，再使用吲哚美辛六天。双氯芬酸钠和吲哚美辛随机给药。与治疗前相比，两种治疗均改善了疾病状况（p<0.01）。就医生和患者的总体评估而言，吲哚美辛和双氯芬酸钠的疗效之间未发现统计学上的显著差异。两种治疗的耐受性相当。
