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酵母交配型转换过程中产生的重组中间体的解析。

Resolution of recombination intermediates generated during yeast mating type switching.

作者信息

Klar A J, Strathern J N

出版信息

Nature. 1984;310(5980):744-8. doi: 10.1038/310744a0.

DOI:10.1038/310744a0
PMID:6382020
Abstract

Interchromosomal gene conversion between alleles has been shown in yeast frequently to be associated with the recombination of flanking genetic markers. Although this also holds true for gene conversion between two alleles of the yeast mating-type (MAT) locus, initiated by the homothallic switching system, we find no evidence that crossing-over ever accompanies gene conversion between the non-allelic HMR and MAT genes when initiated by this same homothallic switching system.

摘要

等位基因间的染色体间基因转换在酵母中常被证明与侧翼遗传标记的重组有关。尽管由同宗配合转换系统启动的酵母交配型（MAT）位点两个等位基因间的基因转换也是如此，但我们没有发现证据表明，当由这个相同的同宗配合转换系统启动时，非等位的HMR和MAT基因间的基因转换会伴随着交叉现象。

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1
Resolution of recombination intermediates generated during yeast mating type switching.酵母交配型转换过程中产生的重组中间体的解析。
Nature. 1984;310(5980):744-8. doi: 10.1038/310744a0.
2
Homothallic switching of Saccharomyces cerevisiae mating type genes by using a donor containing a large internal deletion.通过使用含有大片段内部缺失的供体实现酿酒酵母交配型基因的同宗转换
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Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination.酵母交配型基因的同宗配合转换通过染色体内重组发生。
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The Saccharomyces cerevisiae recombination enhancer biases recombination during interchromosomal mating-type switching but not in interchromosomal homologous recombination.酿酒酵母重组增强子在染色体间交配型转换过程中会使重组产生偏差，但在染色体间同源重组中则不会。
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Conservative inheritance of newly synthesized DNA in double-strand break-induced gene conversion.双链断裂诱导的基因转换中新合成DNA的保守遗传
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