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酵母交配型转换过程中产生的重组中间体的解析。

Resolution of recombination intermediates generated during yeast mating type switching.

作者信息

Klar A J, Strathern J N

出版信息

Nature. 1984;310(5980):744-8. doi: 10.1038/310744a0.

Abstract

Interchromosomal gene conversion between alleles has been shown in yeast frequently to be associated with the recombination of flanking genetic markers. Although this also holds true for gene conversion between two alleles of the yeast mating-type (MAT) locus, initiated by the homothallic switching system, we find no evidence that crossing-over ever accompanies gene conversion between the non-allelic HMR and MAT genes when initiated by this same homothallic switching system.

摘要

等位基因间的染色体间基因转换在酵母中常被证明与侧翼遗传标记的重组有关。尽管由同宗配合转换系统启动的酵母交配型(MAT)位点两个等位基因间的基因转换也是如此,但我们没有发现证据表明,当由这个相同的同宗配合转换系统启动时,非等位的HMR和MAT基因间的基因转换会伴随着交叉现象。

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