McMahon M J, Woodhead J S, Hayward R D
Br J Surg. 1978 Mar;65(3):216-8. doi: 10.1002/bjs.1800650323.
A retrospective and prospective study was made of 82 attacks of acute pancreatitis occurring in 80 patients. Attacks were defined as mild (55) or severe (27) according to clinical criteria. Severe attacks were associated with significantly low levels of uncorrected calcium and calculated ionized calcium, both at the time of admission and 48 h later. Patients with severe attacks were found to have lower levels of parathyroid hormone than either those with mild attacks or other patients who had undergone an abdominal operation. These results indicate that severe pancreatitis is associated with true hypocalcaemia, and that deficiency of circulating parathyroid hormone may be a factor in its production.
对80例患者发生的82次急性胰腺炎发作进行了回顾性和前瞻性研究。根据临床标准，发作被定义为轻度（55次）或重度（27次）。重度发作在入院时和48小时后，其未校正钙和计算出的离子钙水平均显著降低。发现重度发作患者的甲状旁腺激素水平低于轻度发作患者或其他接受过腹部手术的患者。这些结果表明，重症胰腺炎与真正的低钙血症有关，循环甲状旁腺激素缺乏可能是其产生的一个因素。
