[暴露于失重状态下大鼠的造血状态]
[Hemopoietic status of rats exposed to weightlessness].
作者信息
Shvets V N, Vatsek A, Kozinets G I, Britvan I I, Korol'kov V I
出版信息
Kosm Biol Aviakosm Med. 1984 Jul-Aug;18(4):12-6.
This paper summarizes experimental data on the erythropoiesis of rats flown on Cosmos biosatellites for 18-22 days. The histogenesis of the hemopoietic tissue is investigated at the level of stem cells, dividing-maturing pool and mature blood cells (erythrocytes). In weightlessness inhibition of the erythropoiesis in various skeletal sites occurs. Flight data are compared with hemopoietic findings in hypokinetic rats. Possible mechanisms underlying red blood disorders in humans during space flight are discussed.
本文总结了在宇宙生物卫星上飞行18 - 22天的大鼠红细胞生成的实验数据。在干细胞、分裂成熟池和成熟血细胞（红细胞）水平上研究造血组织的组织发生。在失重状态下，不同骨骼部位的红细胞生成受到抑制。将飞行数据与低动力大鼠的造血研究结果进行了比较。讨论了人类在太空飞行期间红细胞紊乱的潜在机制。
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