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鸟类脂肪组织的代谢及其调控

Adipose tissue metabolism and its control in birds.

作者信息

Leclercq B

出版信息

Poult Sci. 1984 Oct;63(10):2044-54. doi: 10.3382/ps.0632044.

DOI:10.3382/ps.0632044
PMID:6387692
Abstract

At any age, with increases in body weight, the elevation in total lipid or abdominal fat is more than proportional to body weight. This observation explains why selection of broilers for rapid growth rate leads to excessive fat accumulation. Although adipocyte hyperplasia continues until 12 or 14 weeks of age, hypertrophia becomes increasingly important with age and the degree of fattening. The number of adipocytes appears to be correlated with body size, and the size of the adipocyte is closely related to the fat content of the live bird. The hormonal control of lipolysis involves a number of hormones and appears to be very complex. The increase in fat in adipose tissue is mainly due to hepatic lipogenesis. This review discusses the relative role of hormones in fat metabolism, some pecularities of insulin activity in birds, and the important functions of plasma lipoprotein and adipose lipoprotein lipase. A comparison of a fat line of chickens and mammalian models of obesity is also made.

摘要

在任何年龄段,随着体重增加,总脂质或腹部脂肪的升高与体重的增加不成正比。这一观察结果解释了为何选择生长速度快的肉鸡会导致脂肪过度积累。尽管脂肪细胞增生会持续到12或14周龄,但随着年龄增长和育肥程度的增加,肥大变得越来越重要。脂肪细胞的数量似乎与体型相关,而脂肪细胞的大小与活禽的脂肪含量密切相关。脂肪分解的激素控制涉及多种激素,且似乎非常复杂。脂肪组织中脂肪的增加主要归因于肝脏的脂肪生成。本文综述了激素在脂肪代谢中的相对作用、禽类胰岛素活性的一些特点以及血浆脂蛋白和脂肪脂蛋白脂肪酶的重要功能。同时还对肉鸡的脂肪品系与哺乳动物肥胖模型进行了比较。

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