Forestier C, Darfeuille-Michaud A, Joly B
Eur J Clin Microbiol. 1984 Oct;3(5):427-32. doi: 10.1007/BF02017364.
Subinhibitory concentrations of 28 antibiotics were tested for their effects on MRHA patterns of four enterotoxigenic Escherichia coli strains possessing colonization factor antigens CFA/I, CFA/II or CFA/III. Only penicillin G, oleandomycin, doxycycline and minocycline inhibited the haemagglutination pattern of three Escherichia coli strains with CFA/I and CFA/II when added to the medium culture at concentrations ranging from 1/2 to 1/50 of the MIC. At the same concentrations they also decreased the adhesion index of the four strains to human intestinal cells. However, neither the specific agglutination of bacterial cells with CFA antisera nor the production of CFAs was affected.
测试了28种抗生素的亚抑制浓度对4株具有定植因子抗原CFA/I、CFA/II或CFA/III的产肠毒素大肠杆菌菌株MRHA模式的影响。当以MIC的1/2至1/50的浓度添加到培养基培养物中时，只有青霉素G、竹桃霉素、强力霉素和米诺环素抑制了三株具有CFA/I和CFA/II的大肠杆菌菌株的血凝模式。在相同浓度下，它们还降低了这四株菌株对人肠道细胞的粘附指数。然而，细菌细胞与CFA抗血清的特异性凝集以及CFA的产生均未受到影响。
