Cripps A W, Clancy R L, Chipchase H, Hennessy E J
Aust J Exp Biol Med Sci. 1984 Oct;62 ( Pt 5):531-7. doi: 10.1038/icb.1984.50.
The immune function of lymphocytes isolated from human mesenteric lymph nodes (MLN) has been examined. Large yields of viable lymphocytes were obtained from MLN without the need for using enzyme or mucolytic agents. In comparison to gut mucosal lymphocytes, MLN lymphocytes (MLNL) were technically easier to manipulate and to use in providing a more quantitative analysis of T-B cell interaction. The results presented indicate that the pattern of immunoglobulin secretion and immunoregulation of lymphocytes isolated from MLN was similar to that in cells isolated from the lamina propria, supporting that MLN constitute an important component of gut-associated lymphoid tissue (GALT).
已对从人肠系膜淋巴结（MLN）分离出的淋巴细胞的免疫功能进行了检测。无需使用酶或黏液溶解剂即可从MLN获得大量有活力的淋巴细胞。与肠道黏膜淋巴细胞相比，MLN淋巴细胞（MLNL）在技术上更易于操作，并且在对T-B细胞相互作用进行更定量分析时更易于使用。所呈现的结果表明，从MLN分离出的淋巴细胞的免疫球蛋白分泌模式和免疫调节与从固有层分离出的细胞相似，这支持了MLN构成肠道相关淋巴组织（GALT）的重要组成部分。
