轻度镇痛药与急诊科——成本和安全性比效力更重要？
Mild analgesics and the accident and emergency department--cost and safety more important than potency?
作者信息
Yates D W, Laing G S, Peters K, Kumar K
出版信息
Arch Emerg Med. 1984 Dec;1(4):197-203. doi: 10.1136/emj.1.4.197.
Abstract
A prospective controlled trial involving over 1000 patients did not reveal any difference between four drugs commonly used in accident and emergency departments for the relief of mild to moderate pain. There were no significant variations in therapeutic effect, side-effects or patient compliance. When considering the supply of analgesics which may be no more potent than those available without prescription from retail chemists, cost and safety are more important than analgesic effect. By restricting the choice of analgesics available, the accident and emergency department should be able to increase awareness among its staff of the actions and side-effects of a small number of prescribed drugs and to contain costs.
摘要
一项涉及1000多名患者的前瞻性对照试验并未发现急诊科常用的四种缓解轻至中度疼痛的药物之间存在任何差异。在治疗效果、副作用或患者依从性方面没有显著差异。在考虑供应可能并不比从零售药店无需处方就能买到的药物效力更强的镇痛药时，成本和安全性比镇痛效果更重要。通过限制可用镇痛药的选择，急诊科应该能够提高其工作人员对少数处方药的作用和副作用的认识，并控制成本。
相似文献
1
Mild analgesics and the accident and emergency department--cost and safety more important than potency?轻度镇痛药与急诊科——成本和安全性比效力更重要？
Arch Emerg Med. 1984 Dec;1(4):197-203. doi: 10.1136/emj.1.4.197.
2
Peripherally acting analgesics.外周作用性镇痛药。
Am J Med. 1984 Sep 10;77(3A):17-26. doi: 10.1016/s0002-9343(84)80099-6.
3
Mefenamic acid and dextropropoxyphene with paracetamol as analgesics in the accident department.在急诊科，甲芬那酸、右丙氧芬与对乙酰氨基酚作为镇痛药使用。
Curr Med Res Opin. 1977;5(2):189-91. doi: 10.1185/03007997709110163.
4
[Treatment of postoperative pain. Zomepirac, mefenamic acid and placebo].[术后疼痛的治疗。唑美匹拉克、甲灭酸与安慰剂]
MMW Munch Med Wochenschr. 1982 Oct 8;124(40):869-70.
5
Comparative study of mefenamic acid and dextropropoxyphene plus paracetamol in an accident and emergency department.甲芬那酸与右丙氧芬加对乙酰氨基酚在急诊科的对比研究。
Curr Med Res Opin. 1980;7(2):77-84. doi: 10.1185/03007998009112030.
6
Randomised controlled trial of general practitioner versus usual medical care in an urban accident and emergency department: process, outcome, and comparative cost.城市急诊科全科医生与常规医疗护理对比的随机对照试验：过程、结果及成本比较
BMJ. 1996 May 4;312(7039):1135-42. doi: 10.1136/bmj.312.7039.1135.
7
Use of analgesia in severe pain in the accident and emergency department.急诊科中重度疼痛的镇痛治疗应用
Arch Emerg Med. 1987 Mar;4(1):25-31. doi: 10.1136/emj.4.1.25.
8
NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac.非甾体抗炎药在急诊科的使用及疗效：口服布洛芬单剂量与肌肉注射酮咯酸的对比
Ann Pharmacother. 1994 Mar;28(3):309-12. doi: 10.1177/106002809402800301.
9
Double blind comparison of mefenamic acid and acetaminophen (paracetamol) in migraine.甲芬那酸与对乙酰氨基酚（扑热息痛）治疗偏头痛的双盲对照研究
Cephalalgia. 1983 Jun;3(2):129-34. doi: 10.1046/j.1468-2982.1983.0302129.x.
10
A comparative evaluation of marketed analgesic drugs.
N Engl J Med. 1972 Apr 13;286(15):813-5. doi: 10.1056/NEJM197204132861504.
引用本文的文献
1
Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury.口服非甾体抗炎药与其他口服镇痛药治疗急性软组织损伤的比较
Cochrane Database Syst Rev. 2020 Aug 12;8(8):CD007789. doi: 10.1002/14651858.CD007789.pub3.
2
Oral cyclo-oxygenase 2 inhibitors versus other oral analgesics for acute soft tissue injury: systematic review and meta-analysis.口服环氧化酶-2 抑制剂与其他口服镇痛药治疗急性软组织损伤的系统评价和荟萃分析。
Clin Drug Investig. 2010;30(7):419-37. doi: 10.2165/11533350-000000000-00000.
3
Analgesia in the accident and emergency department: do SHOs have the knowledge to provide optimal analgesia?急诊部门的镇痛治疗：住院医师是否具备提供最佳镇痛治疗的知识？
J Accid Emerg Med. 1998 May;15(3):147-50. doi: 10.1136/emj.15.3.147.
4
Efficiency and effectiveness.效率与效果。
Arch Emerg Med. 1985 Sep;2(3):109-12. doi: 10.1136/emj.2.3.109.
5
Use of non-steroidal anti-inflammatory drugs for sprains in the accident and emergency department.非甾体抗炎药在急诊科用于扭伤的情况。
Arch Emerg Med. 1987 Mar;4(1):69-70. doi: 10.1136/emj.4.1.69.
本文引用的文献
1
Comparative study of mefenamic acid and dextropropoxyphene plus paracetamol in an accident and emergency department.甲芬那酸与右丙氧芬加对乙酰氨基酚在急诊科的对比研究。
Curr Med Res Opin. 1980;7(2):77-84. doi: 10.1185/03007998009112030.
2
Effect of restrictions on prescribing patterns for dextropropoxyphene.对右丙氧芬处方模式限制的影响。
Br Med J. 1980 Sep 6;281(6241):651-3. doi: 10.1136/bmj.281.6241.651.
3
Paracetamol, tiaramide and placebo for pain relief after orthopedic surgery.对乙酰氨基酚、替拉米特与安慰剂用于骨科手术后的止痛
Acta Anaesthesiol Scand. 1981 Jun;25(3):209-14. doi: 10.1111/j.1399-6576.1981.tb01638.x.
4
Impact of a drug bulletin on prescribing oral analgesics in a teaching hospital.药物通报对一家教学医院口服镇痛药处方的影响。
Am J Hosp Pharm. 1982 Jan;39(1):98-100.
5
Zomepirac, placebo and paracetamol/dextropropoxyphene combination compared in orthopaedic postoperative pain.
Br J Anaesth. 1982 Sep;54(9):927-33. doi: 10.1093/bja/54.9.927.
6
Neuroendocrine markers of CNS drug effects.中枢神经系统药物作用的神经内分泌标志物。
Br J Clin Pharmacol. 1980 Jul;10(1):5-21. doi: 10.1111/j.1365-2125.1980.tb00497.x.
7
Double blind trial of mefenamic acid, aspirin and placebo in patients with post-operative pain.甲芬那酸、阿司匹林和安慰剂用于术后疼痛患者的双盲试验。
Indian J Med Sci. 1974 Dec;28(12):532-6.
8
Mefenamic acid and dextropropoxyphene with paracetamol as analgesics in the accident department.在急诊科，甲芬那酸、右丙氧芬与对乙酰氨基酚作为镇痛药使用。
Curr Med Res Opin. 1977;5(2):189-91. doi: 10.1185/03007997709110163.
Zotero 插件