Yaniv A, Altiboum Z, Gazit A, Bloch-Shtacher N, Eylan E
Exp Cell Biol. 1978;46(4):220-30. doi: 10.1159/000162897.
A continuous human colon carcinoma cell line (HuCCL-14) was established whose cells possess an epithelial-like morphology and are capable of growing in soft agar and on monolayers of normal cells. HuCCL-14 cells yielded high levels of carcinoembryonic antigen, and the analysis of their chromosomal constitution revealed a mode of 70 chromosomes per cell. HuCCL-14 cells produce malignant tumors when injected into nude mice. Preliminary virologic studies indicate the release of RNA particles having a density of 1.15--1.19 g/ml.
建立了一种连续的人结肠癌细胞系（HuCCL - 14），其细胞具有上皮样形态，能够在软琼脂中以及正常细胞单层上生长。HuCCL - 14细胞产生高水平的癌胚抗原，对其染色体组成的分析显示每个细胞有70条染色体的模式。将HuCCL - 14细胞注入裸鼠时会产生恶性肿瘤。初步病毒学研究表明释放出密度为1.15 - 1.19 g/ml的RNA颗粒。
