Hansman D
J Hyg (Lond). 1983 Feb;90(1):49-54. doi: 10.1017/s0022172400063828.
During the ten-year period 1971-80 isolates of meningococci from 85 cases of meningococcal disease (MD) in South Australia, from 66 children, 6 adolescents and 13 adults, were examined. These comprised 69 cases of meningitis and 16 cases of bacteraemia without meningitis. Thirty-three (39%) of all cases of MD occurred in children less than 1 year of age, the median age was 19 months. Serogroup B accounted for 61 (72%) cases of MD, group A seven (8%), group C seven (8%), group W135 five (6%), group Y three (4%) and group X one (1%); in addition there was a single case of Neisseria lactamica infection. The annual prevalence of MD in South Australia for the period was 11 cases per 100000 for children under the age of 2 years and 0.7 cases per 100000 overall. The prevalence was highest in winter (45% cases) and spring (26%) and lowest in summer (13%). The overall mortality rate was 8%. Four of the 21 infants under the age of 6 months died (mortality rate 19%) whereas none of the 32 children aged from 6 months to 14 years died (P = 0.02). Amongst the survivors, three children had deafness, which was bilateral and severe in two.
在1971年至1980年的十年间，对南澳大利亚州85例脑膜炎球菌病（MD）患者的分离脑膜炎球菌进行了检查，这些患者包括66名儿童、6名青少年和13名成人。其中有69例脑膜炎患者和16例无脑膜炎的菌血症患者。所有MD病例中，33例（39%）发生在1岁以下儿童，中位年龄为19个月。B血清群占MD病例的61例（72%），A群7例（8%），C群7例（8%），W135群5例（6%），Y群3例（4%），X群1例（1%）；此外，还有1例乳酸奈瑟菌感染病例。该时期南澳大利亚州2岁以下儿童MD的年患病率为每100000人中有11例，总体年患病率为每100000人中有0.7例。患病率在冬季最高（占病例的45%），春季次之（26%），夏季最低（13%）。总体死亡率为8%。21名6个月以下婴儿中有4名死亡（死亡率19%），而32名6个月至14岁的儿童均未死亡（P = 0.02）。在幸存者中，有3名儿童失聪，其中2名是双侧严重失聪。
