Fischbach K F
Dev Biol. 1983 Jan;95(1):1-18. doi: 10.1016/0012-1606(83)90002-7.
Golgi staining of neuronal cell types in the optic lobe rudiments of adult eyeless flies of the sine oculis (so) mutant of Drosophila melanogaster reveals partial independence of optic lobe's development from compound eye formation. (1) Differentiation and maintenance of many neuronal cell types of medulla and lobular complex do not require innervation of the medulla from the retina and the lamina. Neurons derived from the outer and inner optic anlage have been found in adult eyeless flies. (2) The rudiments of ipsilateral medulla, lobula, and lobular plate are isotopically connected with each other. (3) Stratification of the lobular complex is retained. (4) Equivalent parts of the dorsal lobulae are connected by heterolateral small field neurons. (5) The shapes of many tangential neurons of the medulla show sprouting and compensatory innervation of the lobular complex. The basic results reported here for eyeless flies have many parallels in what is known about anophthalmic mice.
对黑腹果蝇无眼（so）突变体成年无眼果蝇视叶原基中的神经元细胞类型进行高尔基染色，结果显示视叶的发育在一定程度上独立于复眼形成。（1）髓质和小叶复合体的许多神经元细胞类型的分化和维持并不需要视网膜和神经节层对髓质的神经支配。在成年无眼果蝇中发现了源自外视原基和内视原基的神经元。（2）同侧髓质、小叶和小叶板原基彼此同位素连接。（3）小叶复合体的分层得以保留。（4）背侧小叶的对应部分由异侧小视野神经元连接。（5）髓质中许多切向神经元的形状显示出小叶复合体的发芽和代偿性神经支配。此处报道的无眼果蝇的基本结果与已知的无眼小鼠情况有许多相似之处。
