人结肠黏膜中的激素敏感性腺苷酸环化酶
Hormone-sensitive adenylate cyclase in human colonic mucosa.
作者信息
Simon B, Czygan P, Spaan G, Dittrich J, Kather H
出版信息
Digestion. 1978;17(3):229-33. doi: 10.1159/000198114.
PMID:640273
Abstract
Human colonic adenylate cyclase has been shown to be sensitive to vasoactive intestinal polypeptide (VIP) and prostaglandins of the E- and F-type. Maximal activation of enzyme activity averaged 200% for VIP and 300-350% for the E-prostaglandins. Both classes of hormones had an additive effect on enzyme activity indicating the existence of two distinct hormone-sensitive adenylate cyclases in human colonic mucosa.
摘要
已证明人结肠腺苷酸环化酶对血管活性肠肽（VIP）以及E型和F型前列腺素敏感。酶活性的最大激活程度，VIP平均为200%，E型前列腺素为300 - 350%。这两类激素对酶活性具有相加作用，表明人结肠黏膜中存在两种不同的激素敏感型腺苷酸环化酶。
Zotero 插件