温度和相对湿度对环氧乙烷灭菌用生物指示剂的影响。
Effects of temperature and relative humidity on biological indicators used for ethylene oxide sterilization.
作者信息
Oxborrow G S, Placencia A M, Danielson J W
出版信息
Appl Environ Microbiol. 1983 Feb;45(2):546-9. doi: 10.1128/aem.45.2.546-549.1983.
A study was made to determine the effects of temperature and moisture on the D-value of a common biological indicator. Relative humidity (RH) was varied between 10 and 70% in increments of 10%, and temperature was varied between 30 and 70 degrees C in increments of 10 degrees C. Temperature was found to have a pronounced effect on the D-value. At 60% RH, the D-value varied from 15.0 min at 30 degrees C to 1.1 min at 70 degrees C. When RH was plotted against the average D-value at the various temperatures, the temperature curves at or above 50 degrees C were more erratic and the RH had a significant effect. The study showed that temperature and RH must be controlled if biological indicators are to be properly calibrated for use in ethylene oxide sterilization.
开展了一项研究，以确定温度和湿度对一种常见生物指示剂D值的影响。相对湿度（RH）在10%至70%之间以10%的增量变化，温度在30摄氏度至70摄氏度之间以10摄氏度的增量变化。结果发现温度对D值有显著影响。在60%相对湿度下，D值从30摄氏度时的15.0分钟变化到70摄氏度时的1.1分钟。当将相对湿度与不同温度下的平均D值作图时，50摄氏度及以上的温度曲线更不稳定，相对湿度有显著影响。该研究表明，如果要对生物指示剂进行适当校准以用于环氧乙烷灭菌，就必须控制温度和相对湿度。
Zotero 插件