维生素K对黄曲霉毒素B1（AFB）诱导的三种易受AFB影响的细菌摄氧抑制作用的逆转。

Reversion by vitamin K of aflatoxin B1 (AFB)-induced inhibition of oxygen uptake in three AFB-susceptible bacteria.

作者信息

Uwaifo O A

出版信息

Toxicol Lett. 1983 Jan;15(1):57-60. doi: 10.1016/0378-4274(83)90169-8.

Abstract

The effect of Vitamin K, on the inhibition of oxygen uptake in Bacillus brevis (2611), Bacillus megaterium (1368) and Flavobacterium aurantiacum by aflatoxin B1 (AFB) has been investigated. At 1.5 mM, vitamin K completely reversed oxygen inhibition by 10 micrograms/ml AFB in the three bacteria and by 50 micrograms/ml AFB in B. brevis, the most susceptible of the three bacteria to AFB. Vitamin K did not reverse the inhibitory effect of 100 micrograms/ml AFB in any of the three bacteria except B. megaterium, neither did 1.5 mM 2,4-dinitrophenol (DNP) reverse the inhibition at 10 micrograms/ml and 100 micrograms/ml levels of AFB in any of the three bacteria.

摘要

研究了维生素K对黄曲霉毒素B1（AFB）抑制短短芽孢杆菌（2611）、巨大芽孢杆菌（1368）和橙色黄杆菌氧气摄取的影响。在1.5 mM时，维生素K完全逆转了10微克/毫升AFB对这三种细菌的氧气抑制作用，以及在短短芽孢杆菌（三种细菌中对AFB最敏感的）中50微克/毫升AFB的氧气抑制作用。除巨大芽孢杆菌外，维生素K不能逆转100微克/毫升AFB对这三种细菌中任何一种的抑制作用，1.5 mM的2,4-二硝基苯酚（DNP）也不能逆转10微克/毫升和100微克/毫升水平的AFB对这三种细菌中任何一种的抑制作用。