Young M A, Rowlands D B, Stallard T J, Watson R D, Littler W A
Br Med J (Clin Res Ed). 1983 Apr 16;286(6373):1235-6. doi: 10.1136/bmj.286.6373.1235.
The effect of environment on blood pressure was studied by recording intra-arterial pressure continuously in nine patients with essential hypertension during controlled periods of activity and rest at home and in hospital. Mean systolic pressure was higher at home (152 +/- 16 mm Hg) than in hospital (138 +/- 11 mm Hg, p less than 0.01), the difference being greatest during the period of activity (165 +/- 21 v 142 +/- 13 mm Hg, p less than 0.001); heart rates and diastolic pressures did not differ significantly at these times. Systolic pressure recorded by conventional sphygmomanometry was also higher at home (173 +/- 23 v 159 +/- 23 mm Hg, p less than 0.01), as was diastolic pressure (98 +/- 10 v 89 +/- 11 mm Hg, p less than 0.02). Systolic pressure was consistently higher at home, and this effect was independent of the pressure of an observer. This must be taken into consideration when assessing blood pressure and efficacy of treatment in hospital.
通过对9例原发性高血压患者在家庭和医院进行的活动与休息控制期内连续记录动脉内压力，研究环境对血压的影响。在家时平均收缩压（152±16mmHg）高于在医院时（138±11mmHg，p<0.01），活动期差异最大（165±21 vs 142±13mmHg，p<0.001）；此时心率和舒张压无显著差异。通过传统血压计记录的收缩压在家时也较高（173±23 vs 159±23mmHg，p<0.01），舒张压也是如此（98±10 vs 89±11mmHg，p<0.02）。在家时收缩压始终较高，且这种影响与观察者的压力无关。在评估医院内的血压和治疗效果时必须考虑到这一点。
