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红外线凝固术与橡皮圈套扎术治疗Ⅰ、Ⅱ度痔疮的比较:一项随机前瞻性临床试验

Comparison of infrared coagulation and rubber band ligation for first and second degree haemorrhoids: a randomised prospective clinical trial.

作者信息

Templeton J L, Spence R A, Kennedy T L, Parks T G, Mackenzie G, Hanna W A

出版信息

Br Med J (Clin Res Ed). 1983 Apr 30;286(6375):1387-9. doi: 10.1136/bmj.286.6375.1387.

Abstract

One hundred and thirty seven previously untreated out-patients with first and second degree haemorrhoids were allocated at random to treatment by infrared coagulation (n=66) or rubber band ligation (n=71). Complete follow up was obtained in 122 patients (60 who had undergone infrared coagulation (group 1), and 62 rubber band ligation (group 2)) at periods from three months to one year after completion of treatment. Infrared coagulation produced a satisfactory outcome in 51 patients (85%): 34 were rendered asymptomatic and 17 improved. Rubber band ligation produced a satisfactory outcome in 57 patients (92%): 33 were rendered asymptomatic and 24 improved. Both methods were equally effective in first and second degree haemorrhoids. The incidence of side effects, particularly discomfort, during and after treatment was significantly higher in those treated by rubber band ligation (p less than 0.001). This appeared to be an appreciable deterrent to future patient compliance. The number of patients losing more than 24 hours from work was higher after rubber band ligation than after infrared coagulation. The number of treatments necessary to cure symptoms did not differ significantly between the two methods. Infrared coagulation was significantly faster than rubber band ligation (p less than 0.001). Infrared coagulation is a simple, fast, and effective outpatient method for the treatment of first and second degree haemorrhoids with fewer troublesome side effects and higher patient acceptability than rubber band ligation.

摘要

137例未经治疗的一、二度痔疮门诊患者被随机分为两组,分别接受红外线凝固治疗(n = 66)或橡皮圈套扎治疗(n = 71)。治疗结束后3个月至1年期间,对122例患者(60例接受红外线凝固治疗(第1组),62例接受橡皮圈套扎治疗(第2组))进行了完整随访。红外线凝固治疗使51例患者(85%)获得满意疗效:34例无症状,17例病情改善。橡皮圈套扎治疗使57例患者(92%)获得满意疗效:33例无症状,24例病情改善。两种方法治疗一、二度痔疮同样有效。橡皮圈套扎治疗的患者在治疗期间及治疗后的副作用发生率,尤其是不适感,显著高于红外线凝固治疗组(p < 0.001)。这似乎对患者未来的依从性有明显的阻碍作用。橡皮圈套扎治疗后误工超过24小时的患者人数多于红外线凝固治疗。两种方法治愈症状所需的治疗次数无显著差异。红外线凝固治疗明显比橡皮圈套扎治疗快(p < 0.001)。红外线凝固治疗是一种简单、快速且有效的门诊治疗一、二度痔疮的方法,与橡皮圈套扎治疗相比,副作用较少,患者接受度更高。

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