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[人类淋巴细胞对烷化剂抗增殖作用敏感性的变异性]

[Variability of the sensitivity of human lymphocytes to the antiproliferative action of alkylating agents].

作者信息

Veremko L N, Telegin L Iu, Pevnitskii L A

出版信息

Biull Eksp Biol Med. 1983 May;95(5):73-5.

PMID:6405824
Abstract

A study was made of variability of the sensitivity of peripheral blood lymphocytes from different donors to an antiproliferative action of cyclophosphamide and thiophosphamide. A similar degree of the sensitivity was revealed to alkylating agents differing in the action mode, with this degree being independent of the "stimulation index" magnitude.

摘要

对来自不同供体的外周血淋巴细胞对环磷酰胺和硫磷酰胺抗增殖作用的敏感性变异性进行了研究。结果显示，对作用方式不同的烷化剂具有相似程度的敏感性，且该程度与“刺激指数”大小无关。

相似文献

1
[Variability of the sensitivity of human lymphocytes to the antiproliferative action of alkylating agents].[人类淋巴细胞对烷化剂抗增殖作用敏感性的变异性]
Biull Eksp Biol Med. 1983 May;95(5):73-5.
2
[Sensitivity of the splenic cells of different mouse strains to the antiproliferative action of alkylating compounds].[不同小鼠品系脾细胞对烷化化合物抗增殖作用的敏感性]
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[Genetic heterogeneity of heat shock protein synthesis and sensitivity of spleen cells to the antiproliferative effect of alkylating agents in mice].[小鼠热休克蛋白合成的遗传异质性及脾细胞对烷化剂抗增殖作用的敏感性]
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[Interchangeability of mutagens during fractionated effects of unequal concentrations of alkylating agents].
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[Combined effect of thiophosphamide and dipin on the chromosomes of human lymphocytes].
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Survival of hematopoietic and lymphoma colony-forming cells in vivo following the administration of a variety of alkylating agents.给予多种烷化剂后造血和淋巴瘤集落形成细胞在体内的存活情况。
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