Rhodes R H, Marchildon M B, Luebke D C, Edmondson H A, Mikity V G
Hum Pathol. 1978 Mar;9(2):211-21. doi: 10.1016/s0046-8177(78)80112-9.
The gross, microscopic, and ultrastructural features of a mixed liver hamartoma occurring in a three month old infant are reported. The differentiation from two solid liver masses, focal nodular hyperplasia and liver cell adenoma is emphasized. Mesenchymal hamartomas, though usually cystic rather than solid masses, share the histologic feature of fibroductular tissue with mixed liver hamartomas and focal nodular hyperplasia. Only the mixed liver hamartoma has extremely broad fields of ductules and an embryonic type of hepatocyte at the ultrastructural level. These and other hepatic lesions show morphologic evidence of transformation of liver cells into biliary epithelial cells in association with vascular connective tissue.
报告了一名三个月大婴儿发生的混合性肝错构瘤的大体、显微镜和超微结构特征。强调了其与两种实性肝肿块，即局灶性结节性增生和肝细胞腺瘤的鉴别。间质性错构瘤虽然通常是囊性而非实性肿块，但与混合性肝错构瘤和局灶性结节性增生具有纤维导管组织的组织学特征。只有混合性肝错构瘤在超微结构水平上具有极广泛的小胆管区域和胚胎型肝细胞。这些及其他肝脏病变显示出肝细胞与血管结缔组织相关联转变为胆管上皮细胞的形态学证据。
