• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[硫代磷酰胺诱导人淋巴细胞的非计划合成]

[Unscheduled synthesis induced by thiophosphamide in human lymphocytes].

作者信息

Titenko N V

出版信息

Tsitol Genet. 1983 Mar-Apr;17(2):58-62.

PMID:6407162
Abstract

An unscheduled DNA synthesis in human nonreplicative lymphocytes is shown to follow cell exposure to thiophosphamide at a dose level of 1-10 microgram/ml. Incorporation of 3H-thymidine in the absence of the mutagen is probably due to spontaneous reparative processes. Significant variations are found of spontaneous and thio-phosphamide-induced levels of a reparative DNA synthesis in normal individuals.

摘要

已表明，人体非复制性淋巴细胞在暴露于剂量为1 - 10微克/毫升的硫磷酰胺后会出现非程序性DNA合成。在无诱变剂情况下3H - 胸苷的掺入可能归因于自发修复过程。正常个体中自发的和硫磷酰胺诱导的修复性DNA合成水平存在显著差异。

相似文献

1
[Unscheduled synthesis induced by thiophosphamide in human lymphocytes].[硫代磷酰胺诱导人淋巴细胞的非计划合成]
Tsitol Genet. 1983 Mar-Apr;17(2):58-62.
2
[Unscheduled DNA synthesis in human peripheral blood lymphocytes undergoing combined exposure to gamma irradiation and methylmethane sulfonate].
Tsitologiia. 1986 Oct;28(10):1091-6.
3
[Cytogenetic damage and the degree of reparative synthesis in the lymphocytes of chemical industry workers].
Gig Sanit. 1991 Dec(12):34-6.
4
[Repair synthesis of DNA in normal and leukemic lymphocytes damaged by an alkylating agent. Inhibition of repair synthesis by caffeine. Preliminary report].[烷化剂损伤的正常及白血病淋巴细胞中DNA的修复合成。咖啡因对修复合成的抑制作用。初步报告]
Schweiz Med Wochenschr. 1974 Jan 26;104(4):149.
5
[Relationship between the cytogenetic effect of different concentrations of thiophosphamide and phosphemide and the duration of their contact with human lymphocytes].
Genetika. 1976;12(6):142-9.
6
[Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments].[萘普生对人淋巴细胞DNA合成及DNA修复的体内实验效应]
Arzneimittelforschung. 1975 Feb;25(2A):291-2.
7
[Comparison of the frequency of chromosome aberrations induced by thiophosphamide in rabbit lymphocytes in vitro and in vivo].[硫代磷酰胺在体外和体内诱导兔淋巴细胞染色体畸变的频率比较]
Biull Eksp Biol Med. 1982 Aug;94(8):90-2.
8
[Proliferative activity of lymphocyte cultures due to the mutagenic action of thiophosphamide in vivo and in vitro].[硫磷酰胺体内外诱变作用导致淋巴细胞培养物的增殖活性]
Biull Eksp Biol Med. 1983 Dec;96(12):89-90.
9
Unscheduled DNA synthesis in human lymphocytes treated with neocarzinostatin.用新制癌菌素处理的人淋巴细胞中的非预定DNA合成。
Gan. 1975 Aug;66(4):441-4.
10
[Effect of the lymphocyte storage conditions on the frequency of chromosome aberrations induced by continuous and fractionated thiophosphamide action].[淋巴细胞储存条件对连续和分次给予硫代磷酰胺作用诱导的染色体畸变频率的影响]
Tsitol Genet. 1982 Mar-Apr;16(2):46-50.