Degoulet P, Menard J, Vu H A, Golmard J L, Devries C, Chatellier G, Plouin P F
Br Med J (Clin Res Ed). 1983 Jul 9;287(6385):88-93. doi: 10.1136/bmj.287.6385.88.
Poor compliance with appointments and drug treatment is one of the recognised factors preventing effective management of hypertension. Factors predictive of poor attendance and inadequate blood pressure control in patients attending a hypertension clinic were therefore determined using univariate analyses and a multivariate logistic model. Out of 1346 patients with blood pressure exceeding 160/95 mm Hg followed up for three years, 209 (15.5%) dropped out during the first year. Variables that were significantly related to increased drop out rates were male sex, young age, obesity at entry, cigarette smoking, direct referral to the clinic as a result of screening instead of referral by a general practitioner, absence of pre-existing antihypertensive treatment at the first visit, moderate hypertension, and low socioeconomic category. Variables at entry that were significantly related to poor blood pressure control at one year were old age, evidence of coronary heart disease, severe hypertension, and raised blood glucose concentrations. Early detection of patients at high risk of drop out or poor blood pressure control might improve treatment of hypertension and allow management to be more individually adapted to each patient.
预约和药物治疗依从性差是公认的妨碍有效控制高血压的因素之一。因此,通过单因素分析和多因素逻辑模型确定了高血压门诊患者中预测就诊率低和血压控制不佳的因素。在1346例血压超过160/95 mmHg且随访三年的患者中,209例(15.5%)在第一年失访。与失访率增加显著相关的变量包括男性、年轻、入组时肥胖、吸烟、因筛查而非由全科医生转诊直接进入门诊、首次就诊时无既往抗高血压治疗、中度高血压和社会经济地位低。入组时与一年时血压控制不佳显著相关的变量包括老年、冠心病证据、重度高血压和血糖浓度升高。早期发现有失访或血压控制不佳高风险的患者可能会改善高血压治疗,并使管理更能针对每个患者进行个体化调整。