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恰加斯病中的免疫球蛋白及其他血清学参数:慢性消化型中IgA水平升高的证据。

Immunoglobulins and other serological parameters in Chagas' disease: evidence for increased IgA levels in the chronic digestive form.

作者信息

Sá Ferreira J A, Galvão-Castro B, Macedo W, Castro C

出版信息

Clin Exp Immunol. 1983 May;52(2):266-70.

Abstract

Immunoglobulin levels were measured in serum samples from 36 patients with different clinical forms of chronic Chagas' disease. Increased IgA levels were observed in 50% of the patients in the chronic digestive group and there was a significant correlation with the severity of the disease. IgG and IgM levels were within the normal range. Anti-ssDNA antibodies and EVI (endothelium, vessels and interstitium) antibodies were found in some patients with different clinical forms of the disease.

摘要

对36例不同临床类型的慢性恰加斯病患者的血清样本进行了免疫球蛋白水平检测。在慢性消化型组中,50%的患者观察到IgA水平升高,且与疾病严重程度存在显著相关性。IgG和IgM水平在正常范围内。在一些不同临床类型的疾病患者中发现了抗单链DNA抗体和EVI(内皮、血管和间质)抗体。

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