Weiss T, Dorow P, Felix R
Rofo. 1983 Jun;138(6):716-21. doi: 10.1055/s-2008-1055816.
The degree of alveolar deposition of inhaled microparticles, which is affected by airway patency, was studied in 16 asymptomatic smokers with small airways disease. Compared to healthy subjects (n = 12) as well as to patients with chronic obstructive lung disease (COLD, n = 14) significant differences in mean alveolar particle deposition were encountered. The results indicate that in both patient groups the lower-lung regions were most affected by airway obstruction. In patients with peripheral airways disease there was no difference in the degree of right- and left-lung aerosol deposition whereas in patients with COLD obstructive airway alteration was found to affect preferably the right lung region.
在16名患有小气道疾病的无症状吸烟者中，研究了受气道通畅性影响的吸入微粒的肺泡沉积程度。与健康受试者（n = 12）以及慢性阻塞性肺疾病（COLD，n = 14）患者相比，平均肺泡颗粒沉积存在显著差异。结果表明，在这两组患者中，下肺区域受气道阻塞的影响最大。在外周气道疾病患者中，左右肺气溶胶沉积程度没有差异，而在COLD患者中，阻塞性气道改变主要影响右肺区域。
