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[血管活性药物与外淋巴中的氧含量(作者译)]

[Vasoactive drugs and oxygen content in the perilymph (author's transl)].

作者信息

Yagi N, Fisch U

出版信息

HNO. 1978 Mar;26(3):90-3.

PMID:640870
Abstract

The effect of different vasodilating drugs on the perilymphatic oxygen content in the cat has been examined by means of the polarographic method. The drugs used such as Papaverin, Rheomacrodex, Ronicol, Praxilen and Lasix have had no significant effect on the oxygen concentration in the perilymph. Histamin, 7% Na2CO3 and 50% glycerol have produced a diminution of the perilymphatic oxygen tension. Only angiotensin has produced a 20% rise of the oxygen pressure in the perilymph. This effect is, however, five times smaller than that reached by inhalation of 5% CO2 and 95% O2.

摘要

采用极谱法研究了不同血管扩张药物对猫外淋巴氧含量的影响。所用药物如罂粟碱、低分子右旋糖酐、烟浪丁、普拉西仑和速尿对外淋巴中的氧浓度无显著影响。组胺、7%碳酸钠和50%甘油可使外淋巴氧张力降低。只有血管紧张素可使外淋巴中的氧压升高20%。然而,这种作用比吸入5%二氧化碳和95%氧气所达到的作用小5倍。

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