外淋巴氧张力与血管活性药物
Perilymphatic oxygen tension and vasoactive drugs.
作者信息
Yagi N, Fisch U, Murata K
出版信息
Ann Otol Rhinol Laryngol. 1978 May-Jun;87(3 Pt 1):364-9. doi: 10.1177/000348947808700314.
The oxygenation of the perilymph in response to the intravenous injection of vasoactive drugs has been measured in 67 cats using the polarographic method. Of all drugs used, only angiotensin induced a significant raise of perilymphatic PO2. Histamine, 50% glycerol and 7% Na2CO2 reduced the perilymphatic PO2. Papaverine, furosemid, pyridylcarbinol, naftidrofuryl and low molecular dextran have no significant effect upon the perilymphatic oxygen tension. Rapid changes of systemic blood pressure were found to correlate with subsequent modifications of the oxygen tension in the perilymphatic space.
采用极谱法在67只猫身上测量了静脉注射血管活性药物后外淋巴的氧合情况。在所有使用的药物中，只有血管紧张素能使外淋巴PO2显著升高。组胺、50%甘油和7% Na2CO2可降低外淋巴PO2。罂粟碱、速尿、吡啶甲醇、萘呋胺酯和低分子右旋糖酐对外淋巴氧张力无显著影响。发现全身血压的快速变化与外淋巴间隙氧张力的后续变化相关。
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