Schlumpf U, Meyer M, Ulrich J, Friede R L
Arthritis Rheum. 1983 Jul;26(7):825-31. doi: 10.1002/art.1780260702.
Two patients developed a Guillain-Barre-like syndrome and a third suffered neuropathy and myokymia during therapy with sodium aurothiomalate. The cumulative dose at the time of development of neuropathy was different in all 3 cases. Evidence for gold toxicity was suggested by clinical, electromyographic, and histologic findings, as well as the disappearance of symptoms and signs on cessation of gold injections.
两名患者在接受硫代苹果酸金钠治疗期间出现了格林-巴利综合征样综合征,第三名患者在治疗期间出现了神经病变和肌纤维颤搐。在所有3例病例中,出现神经病变时的累积剂量各不相同。临床、肌电图和组织学检查结果,以及停止注射金剂后症状和体征消失,均提示存在金中毒。