Gladden L B, Welch H G
J Appl Physiol Respir Environ Exerc Physiol. 1978 Apr;44(4):564-70. doi: 10.1152/jappl.1978.44.4.564.
This study was undertaken to compare the efficiency of aerobic and anaerobic work. Nine subjects worked at approximately 100% VO2 max for 2 min while inspiring gas mixtures with O2 fractions ranging from 0.13 to 0.21. Exercise O2 uptake, recovery O2 uptake, and blood lactate concentration were measured. Steady level O2 uptake was measured in normoxia at submaximal loads of about 30, 50, and 70% of VO2 max. Fast recovery O2 uptake did not change as PIO2 was varied. Exercise O2 uptake and blood lactate concentrations were linearly related to PIO2. The ratio of the slopes of these lines provided an empirical expression of the O2 equivalent of blood lactate. This ratio was constant, suggesting that it is not less efficient to use ATP synthesized anaerobically. Energy input from lactate was calculated using this factor. Efficiency decreased as power output increased even at the submaximal work rates. This may result from either 1) a decrease in muscle efficiency, 2) an increase in metabolism that is not directly related to the external work, or 3) some combination of 1 and 2.
本研究旨在比较有氧和无氧工作的效率。九名受试者在吸入氧气分数范围为0.13至0.21的混合气体时,以约100%的最大摄氧量工作2分钟。测量运动摄氧量、恢复摄氧量和血乳酸浓度。在常氧条件下,以约最大摄氧量的30%、50%和70%的次最大负荷测量稳定状态摄氧量。快速恢复摄氧量并不随吸入氧分压的变化而改变。运动摄氧量和血乳酸浓度与吸入氧分压呈线性相关。这些直线斜率的比值提供了血乳酸氧当量的经验表达式。该比值是恒定的,表明使用无氧合成的三磷酸腺苷并非效率更低。利用该因子计算乳酸的能量输入。即使在次最大工作率下,效率也随着功率输出的增加而降低。这可能是由于以下原因之一:1)肌肉效率降低;2)与外部工作无直接关系的代谢增加;或3)1和2的某种组合。