阿克罗沙星治疗单纯性淋病。
Acrosoxacin in the treatment of uncomplicated gonorrhoea.
作者信息
Walsh R J, Scott R, Bittiner J B, Shahidullah M, Slack R C
出版信息
Br J Vener Dis. 1983 Aug;59(4):242-4. doi: 10.1136/sti.59.4.242.
Acrosoxacin was given as a single 300 mg oral dose to 105 patients with acute gonorrhoea. Of the 100 patients followed completely there was a 93% cure rate and 33% of men developed postgonococcal urethritis (PGU). This compared with a 97% cure and 30% PGU with 2 megaunits penicillin. The in vitro activity of acrosoxacin in Nottingham against strains of Neisseria gonorrhoeae showed that it was a highly active agent with 90% of strains inhibited by a concentration of 0.03 mg/l.
对105例急性淋病患者给予单次口服300毫克阿克罗沙星。在100例得到完整随访的患者中，治愈率为93%，33%的男性发生了淋菌性尿道炎后尿道炎（PGU）。相比之下，200万单位青霉素治疗的治愈率为97%，PGU发生率为30%。阿克罗沙星在诺丁汉对淋病奈瑟菌菌株的体外活性表明，它是一种高效活性药物，90%的菌株在浓度为0.03毫克/升时受到抑制。
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