Iraci G, Gerosa M, Scanarini M, Tomazzoli L, Fiore D L, Pardatscher K, Rigobello L, Secchi A G
Childs Brain. 1980;7(6):314-24. doi: 10.1159/000119959.
5 patients with gliomas of the anterior optic pathways, histologically assessed or with strong diagnostic evidence, who developed precocious or pseudoprecocious puberty (2 cases) before the operation or after radiation treatment, are presented. Only 2 patients presented familial and/or personal evidence of neurofibromatosis. The production mechanism of these sexual changes is discussed.
本文报告了5例组织学确诊或有强有力诊断依据的视交叉前胶质瘤患者,他们在手术前或放疗后出现了性早熟或假性性早熟(2例)。仅2例患者有神经纤维瘤病的家族史和/或个人病史。文中讨论了这些性征改变的发生机制。