Goldberg R J
Hosp Pract (Off Ed). 1983 Aug;18(8):177-81, 184-6, 188-9. doi: 10.1080/21548331.1983.11702619.
The trend in clinical research today is toward increasing reliance on quantitative epidemiologic methods. To evaluate the validity of studies based on epidemiologic principles and their applicability to clinical practice, a working knowledge of the most commonly used observational and experimental study designs is useful. Characteristics of three basic study designs are discussed.
当今临床研究的趋势是越来越依赖定量流行病学方法。为了评估基于流行病学原理的研究的有效性及其在临床实践中的适用性，了解最常用的观察性和实验性研究设计的实用知识是很有帮助的。本文讨论了三种基本研究设计的特点。
