Bryan R N, Lewis R A, Miller S L
AJNR Am J Neuroradiol. 1983 May-Jun;4(3):491-4.
Choroidal osteomas are benign, juxtapapillary, choroidal tumors that mandate no treatment. They occur predominantly in young (median age, 20 years) females (90%). While ophthalmoscopy and fluorescein angiography reveal suggestive ophthalmic findings, echography, plain radiography, and especially computed tomography (CT) are important in establishing the correct diagnosis. These lesions may be clinically confused with various dystrophic lesions, atypical or amelanotic malignant choroidal melanoma, metastatic carcinoma, leukemic or lymphomatous infiltrates, choroidal hemangioma, choroidal scars of the macula, and organized subretinal hemorrhage. The exclusion of the differential consideration of malignant melanoma is most important since radiation and enucleation are therapeutic possibilities. Review of the literature shows that all nine reported cases with CT scans had clearly demonstrable calcific densities in the posterior pole of the affected eye. Four other cases are reported here with a summary of the typical clinical, radiologic, and pathologic findings. The role of CT in the evaluation of choroidal osteoma and the distinctiveness of the CT findings are stressed.
脉络膜骨瘤是一种良性、邻近视乳头的脉络膜肿瘤,无需治疗。它们主要发生于年轻女性(中位年龄20岁),女性占90%。虽然检眼镜检查和荧光素血管造影可显示提示性的眼科表现,但超声检查、X线平片,尤其是计算机断层扫描(CT)对于确立正确诊断很重要。这些病变在临床上可能会与各种营养不良性病变、非典型或无色素性脉络膜恶性黑色素瘤、转移性癌、白血病或淋巴瘤浸润、脉络膜血管瘤、黄斑区脉络膜瘢痕以及机化的视网膜下出血相混淆。排除恶性黑色素瘤的鉴别诊断最为重要,因为放射治疗和眼球摘除是可能的治疗方法。文献回顾显示,所有9例报告的CT扫描病例在患眼后极均有明显可显示的钙化密度。本文报告另外4例病例,并总结典型的临床、放射学和病理学表现。强调了CT在脉络膜骨瘤评估中的作用以及CT表现的独特性。